Duff completed nine passes for 193 yards, while Miskewicz and Joe Poleto combined to rush for 136 yards for Colonie, which plays LaSalle Friday night
"We need to put four quarters together, and we need to be consistent in all phases (against LaSalle)," said Ambrosio.
In other weekend football action, Shaker (1-1) bounced back from its opening week loss to Troy with a 24-7 Liberty Division victory at Columbia, while Saratoga throttled Christian Brothers Academy 47-7 in an Empire Division contest in Colonie.
Columbia (0-2) got on the scoreboard first with a 28-yard touchdown pass from Bobby Smith to Bobby Sarubbi, but Shaker's defense shut the Blue Devils down the rest of the way to pick up its first win of the season.
"The (defensive) scheme was there (against Troy)," said Shaker coach Dennis Bender. "The biggest thing was personnel. We had a lot of guys playing both ways (offense and defense), and they ran out of gas. We had more fresh kids and more kids playing (against Columbia), and that helped us. The kids also stepped up."
One player who stepped up for Shaker was Mark Ambrosio. The junior returned a second quarter punt 74 yards for the go-ahead touchdown, and he added a third quarter interception that set up the Blue Bison's second touchdown " a 23-yard scoring strike from Ryan Gifford to Eric Breton.
"Mark has always been a big-play guy at every level he's played," Bender said of Ambrosio, who is the son of Colonie's head coach Mike Ambrosio. "He's been the MVP at the freshman level, and he was the MVP at the junior varsity level."
Gifford added a seven-yard touchdown run late in the third quarter to seal the win for Shaker, which hosts Niskayuna Friday.
At CBA, the Brothers' defensive struggles continued against Saratoga. The Blue Streaks (1-1) rushed for 322 yards and five touchdowns, including three from Tony DeLoatch and two from Jimmy Minogue. DeLoatch also had an 80-yard kickoff return, and Minogue added a 94-yard touchdown pass to Ryan Quinn.
Andrew Vivian scored CBA's lone touchdown on a one-yard run in the fourth quarter.
The Brothers (0-2) visit Albany Saturday at Bleecker Stadium.""